Ads placed near rich content and navigational aids usually do well because users are focused on those areas of a page. Guess how ads will behave on different pages, and what will be most useful and visible to them. You'll find that the most optimal ad position isn't always what you expect on certain pages.

So, where are the best locations for your Google AdSense ads? Well, I have found the number one best place for the ads are near or in proximity to your main menu. Why near your main menu? Because you know that visitors eyes will and always look for the menu structure of your website. So the common places for placement should be to the top right, the very top under your menu, or the top left. These are the most common locations for your main menu.

But what about the color scheme of the Google AdSense ads? Yes, color is very important. You have to make the ads looks as seamless as possible. You may find that colors that blend with the background completely with font color same as your text and compliments the site perform better, because it seems that ad is the part of the content of the page.
 

By using these tactics I was able to increase my AdSense click through rate significantly depending on traffic level and people's interest.

Take my advice and give it try. I believe you will see a change and hopefully make AdSense a more pleasurable experience and earn more money with the program..